Treatment of Swine Closed Head Injury with PerfluorocarbonNanO2 may assist in mitigating secondary cellular brain damage after traumatic brain injury.
DDFPe as a Resuscitation Fluid for Hemorrhagic Shock and Traumatic Brain Injury: A ReviewAnimal studies, for both hemorrhagic shock and TBI, show promising effects of DDFPe as a resuscitation fluid.
DDFPe reduced secondary brain injury in a Swine Model of Traumatic Brain InjuryIn this swine model of TBI, administration of DDFPe resulted in lower injury scores for spongiosis and ischemic neurons.
DDFPe increased cerebral oxygen tension after traumatic brain injury in rats.DDFPe increased brain tissue oxygen tension following TBI in rats and should be evaluated further as a possible treatment for TBI.
Effects of DDFPe on cerebral microvasculature in the healthy rat.asoconstriction in cerebral pial arterioles of healthy rats.